Defeat Borderlands 3 Tyreen: How to defeat the final boss!


In our guide you will learn, among other things:

  • which weapons are effective in battle
  • which attacks Tyreen uses
  • from which level you are ready for Tyreen

Borderlands 3 challenges you with many strong bosses. After you have already fought Katagawa Ball, Katagawa Jr., Rampager, Aurelia, Agonizer 9000 and Troy Calypso, Tyreen will stand in your way. You can find out which attacks await you and what the reward looks like in our guide to Borderlands 3.

Adjusting the build might help you in the fight against Tyreen. We have collected the best Borderlands 3 Zane builds, builds for Beastmaster FL4K, Borderlands 3 Amara builds and builds for Borderlands 3 Shooter Moze in the linked guides. For more valuable tips, check out the ultimate Borderlands 3 tips guide.

Defeat Tyreen the Destroyer in Borderlands 3: The most important facts

After raging your way through masses of Children of the Chamber followers, the gameplay seamlessly transitions from the Pyre of Stars quest to the Divine Retribution quest. Tyreen appears on the scene and becomes the goddess during the cinematic, who wants to bring about the end of all times.

With any luck, Tyreen's death will reward you with the King's Call and Queen's Call pistols, with each critical hit recharging the magazine. By defeating Tyreen, you'll also complete the Gold Trophy "I never liked her" and get a lot closer to the Platinum Trophy. For an overview of all the trophies in Borderlands 3, check out the linked guide.

Prepare yourself by filling the magazines of your weapons at the vending machines and put on your best equipment. For combat, we recommend a rocket launcher and other weapons that deal the highest possible damage in a short time and can be used at medium or long range. Due to the size of the chamber guard Tyreen has taken possession of, a shotgun does more damage than a pistol.

A powerful Assault Rifle or SMG are ideal for combat. Fire and kinetic damage will take Tyreen down as quickly as possible. Weapons with corrosion and shock damage are not recommended for combat, these do very little damage due to the lack of armor and shields. You can find everything about elemental effects in the Borderlands 3 Tips Guide.

You face Tyreen on a small platform from which there is no escape. Her size and area attacks look very threatening. It's important not to panic, concentrate on dodging and keep the highest possible distance. Move either counterclockwise or clockwise and do not change direction.

Tyreen the Destroyer: How to survive the fight

As in most boss fights, Tyreen doesn't get through the fight without allies. Varkids provide air support and cause additional damage. Do not kill them until you are down. This way, you'll unlock the second chance and won't die immediately if you make a mistake. Tyreen attacks with a homing laser that follows you slowly.

Dodge to the left or right and always keep an eye on her. When her hands touch the ground, pink crystals sprout emerge from the ground in several rows. Do not stop and move in one direction, then most of the crystals will miss you. Periodically she collapses and does not act for a short time.

Lilith calls attention to this and asks you to climb her back. Switch to a powerful shotgun as you mount the beast and courageously shoot the pink glowing eye. This will cause Tyreen's head to come out. Jump down to the front, attack her head with action skills, grenades, a shotgun or a rocket launcher.

After a few seconds, her head disappears back inside the chamber guard. Tyreen flies into the air and summons a huge fireball that channels several flame lasers onto the ground. The beams rotate in a clockwise direction. By moving between the beams, you escape the damage. As the fight goes on and Tyreen's life bar decreases, the damage she deals always increases.

Be especially vigilant at 33 percent remaining life. Just before she dies, two giant fireballs appear, connected to several lasers. They fly over the entire platform. Immune yourself or jump over the thin laser beams to avoid getting hit. In True Vault Hunter mode, Tyreen uses this attack more often.

More tips for fighting the boss of Borderlands 3

  • Tyreen is at level 39, so we recommend at least level 37 for the fight.
  • Her head is her weak point. Hits against weak points are always critical and cause increased damage.
  • Play especially carefully, as there are no chests on the platform. The Varkids occasionally drop ammo and life energy.

We hope that our guide to Tyreen could help you. You can also get some golden chest keys with shift codes in Borderlands 3.

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